- HD 1080
- Runtime: 86m.
- Status: Released
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- Languages: en
- Country: United States of America
- Director: Frank Henenlotter
- Stars: Rick Hearst, Jennifer Lowry, Gordon MacDonald, Theo Barnes, John Zacherle
- keywords: hallucination, addiction, public restroom, parasite, withdrawal, high, subway train, metaphor, 1980s, hookup, euphoria, communal shower
- Production_studio: Palisades Partners, Levins-Henenlotter Productions
- Slogan: It's a Headache from Hell.
- providers: Screambox, Night Flight Plus, Fandor Amazon Channel, Screambox Amazon Channel, ARROW
- The Brain Damage is featured in the top rankings of 1988
- #40 in Top Comedy Movies of 1988
- #12 in Top Horror Movies of 1988
Brian comes under the addictive spell of a parasite with the ability to induce euphoric hallucinations in its hosts.