- HD 1080
- Runtime: 89m.
- Status: Released
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- Languages: en
- Country: United States of America
- Director: Lee Alan McConnell
- Stars: William Zabka, Dana Ashbrook, Alex Jolig, Simmone Mackinnon, Marcus Aurelius
- keywords: creature
- Production_studio: Unified Film Organization, Syfy
- Slogan: The beast is back.
- The Python 2 is featured in the top rankings of 2002
- #37 in Top Horror Movies of 2002
A man, his business partner, and his wife are enlisted to transport an unknown object from a Russian military base, only to discover that the object is a giant, genetically-altered python.