- HD 1080
- Runtime: 90m.
- Status: Released
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- Languages: en
- Country: United States of America, Bulgaria, Germany
- Director: Bruce Campbell
- Stars: Bruce Campbell, Tamara Gorski, Ted Raimi, Antoinette Byron, Stacy Keach
- keywords: operation, taxi driver, comic book, face operation, bulgaria, head injury, doctor
- Production_studio: ApolloProScreen
- Slogan: He's losing their minds
- providers: Amazon Prime Video, Amazon Prime Video with Ads
- The Man with the Screaming Brain is featured in the top rankings of 2005
- #66 in Top Horror Movies of 2005
The brains of a Russian taxi driver and a wealthy businessman are brought together in one body by a mad scientist.