- HD 1080
- Runtime: 88m.
- Status: Released
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- Languages: en
- Country: United States of America
- Director: Barry Jenkins
- Stars: Wyatt Cenac, Tracey Heggins, Elizabeth Acker, Melissa Bisagni, DeMorge Brown
- keywords: one-night stand
- Production_studio: Bandry, Strike Anywhere
- providers: AMC Plus Apple TV Channel, AMC+ Amazon Channel, AMC+, MUBI, MUBI Amazon Channel, IFC Films Unlimited Apple TV Channel
- The Medicine for Melancholy is featured in the top rankings of 2009
- #91 in Top Romance Movies of 2009
Waking from a one-night stand that neither remembers, Micah and Joanne find themselves wandering the streets of San Francisco, sharing coffee and conversation and searching for a deeper connection.