- HD 1080
- Runtime: 80m.
- Status: Released
- 1
- Languages: en
- Country: United States of America
- Director: Lloyd Bacon
- Stars: Jeff Chandler, Faith Domergue, Lyle Bettger, Peter Whitney, Stacy Harris
- keywords: sioux wars
- Production_studio: Universal International Pictures
- Slogan: For the scarlet lips of a traitor's woman - he stood alone - against the mighty Chief Red Cloud and the scalp-hungry hordes at his command!
- The The Great Sioux Uprising is featured in the top rankings of 1953
- #27 in Top Western Movies of 1953
During the Civil War, in Wyoming, horse dealers Joan Britton and Stephen Cook are competing to supply the Union Army with horses. A Cherokee is in the area to stir up the Sioux against the Union just as Cook decides to steal a herd of Sioux horses. Ex-army doctor Jonathan Westgate opposes Cook’s unscrupulous methods as well as being Cook’s rival for the affections of Joan. It seems Westgate is the only one able to prevent a new Indian war.