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Top 100 Mad Scientist movies

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The Ape (1940)

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Dr. Bernard Adrian is a kindly scientist who seeks to cure a young woman's polio. He needs human spinal fluid to complete the formula for his experimental serum. Meanwhile, a vicious circus ape has broken out of its cage, and is terrorizing the townspeople. Can there be a connection?

The Man They Could Not Hang (1939)

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Dr. Henryk Savaard is a scientist working on experiments to restore life to the dead. When he is unjustly hanged for murder, he is brought back to life by his trusted assistant. Re-animated he turns decidedly nasty and sets about murdering the jury that convicted him.

The Phantom Creeps (1939)

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A mad scientist attempts to rule the world by creating various elaborate inventions.

Werewolf of London (1935)

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A strange animal attack turns a botanist into a bloodthirsty monster.

Bride of Frankenstein (1935)

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Dr. Frankenstein and his monster both turn out to be alive, not killed as previously believed. Dr. Frankenstein wants to get out of the evil experiment business, but when a mad scientist, Dr. Pretorius, kidnaps his wife, Dr. Frankenstein agrees to help him create a new creature.

The Invisible Man (1933)

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Working in Dr. Cranley's laboratory, scientist Jack Griffin was always given the latitude to conduct some of his own experiments. His sudden departure, however, has Cranley's daughter Flora worried about him. Griffin has taken a room at the nearby Lion's Head Inn, hoping to reverse an experiment he conducted on himself that made him invisible. But the experimental drug has also warped his mind, making him aggressive and dangerous. He's prepared to do whatever it takes to restore his appearance.

Doctor X (1932)

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A wisecracking New York reporter intrudes on a research scientist's quest to unmask The Moon Killer.

Island of Lost Souls (1932)

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An obsessed scientist conducts profane experiments in evolution, eventually establishing himself as the self-styled demigod to a race of mutated, half-human abominations.

The Drums of Jeopardy (1931)

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A mad doctor is determined to take revenge on the family he believes is responsible for his daughter's death.

Metropolis (1927)

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In a futuristic city sharply divided between the rich and the poor, the son of the city's mastermind meets a prophet who predicts the coming of a savior to mediate their differences.